When your Pap smear is positive
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The likely culprits
About 3 to 5 percent of women experience an abnormal Pap smear -- a test for cervical cancer -- at some point in their lives. Cervical cancer is the most unlikely cause; in fact, everything from a yeast infection to the human papillomavirus (HPV), a sexually transmitted disease, can result in an abnormal Pap smear. Here are possible reasons for an abnormal Pap smear and the latest treatments: --Deborah Pike Olsen
| Type of abnormality: | What it means: | Treatment: |
| Atypical squamous cells of unknown significance (ASCUS) | Your Pap smear wasn't completely normal, but did not meet diagnostic criteria for a lesion. | Your doctor has three options: repeat your Pap test in three to six months, test you for HPV or perform a colposcopy, a visual inspection of the cervix. |
| Low-grade squamous intraepithelial lesion (LSIL) | You have a precancerous lesion caused by HPV. | More than half of these lesions disappear on their own within 24 months. Still, your doctor should perform a colposcopy. |
| High-grade squamous intraepithelial lesion (HSIL) | You have a more serious precancerous lesion caused by HPV. | Your doctor will remove tissue or destroy the abnormal cells. A biopsy is taken to rule out cancer. This treatment is typically effective. |
| Atypical glandular cells | You may have a precancerous condition or cancer of the cervix or uterus. This represents less than 10% of abnormal Pap smears. | A colposcopy is performed, and a biopsy is taken. In premenopausal women with a negative biopsy, Pap smears are repeated every three months. |
| Adenocarcinoma | You have cervical cancer. | In early stages, removal of cervix and possibly uterus; for advanced cancers, removal of both, plus radiation. |
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